SOLITHROMYCIN INHIBITS IL-13-INDUCED GOBLET CELL HYPERPLASIA AND MUC5AC, CLCA1, AND ANO1 IN HUMAN BRONCHIAL EPITHELIAL CELLS

Solithromycin inhibits IL-13-induced goblet cell hyperplasia and MUC5AC, CLCA1, and ANO1 in human bronchial epithelial cells

Solithromycin 3282770208962 is a novel fluoroketolide antibiotic belonging to the class of macrolide antibiotics.Activation of the interleukin (IL)-13 receptor leads to STAT6 activation and subsequent induction of SAM pointed domain containing ETS transcription factor (SPDEF), chloride channel accessory 1 (CLCA1), and anoctamin-1 (ANO1), all of whi

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An Investigation Of Roof Garden Design Criteria

With the effects inflicted by irregular development and growth of built environment that started to form towards the end of the 20th century, green areas started to lose their original function and started to decrease.Higher cost of land in urban areas have led to a re-evaluation of the usable space on building roofs.Accordingly, the number of desi

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